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Compound GL (GL for Ganoderma lucidum) was devised for patients having a diagnosis of chronic fatigue syndrome, a poorly defined condition that may last for a few months to several years. The dominant complaints are immune deficiency (easy to get an illness and having chronic infections), mental agitation and insomnia (contributing to fatigue and disability, possibly depression), and digestive disturbance (the individual reacts adversely to a number of common foods). Therefore, the formula includes immune tonics with sedative nature (e.g., ganoderma, ginseng, schizandra) along with other calming herbs (succinum, zizyphus, and polygala), plus herbs for promoting digestion (pogostemon, atractylodes, ginger) and herbs for alleviating acute symptoms (cyperus, lonicera, hu-chang). Emotional distress and anxiety attacks are common in persons with chronic fatigue; this formula overlaps that anti-anxiety formula Salvia-Amber Tablets with salvia, succinum (amber), zizphus, and ginseng. The herbs in this formula were selected for their mild nature and the fact that most people, even those with many food sensitivities, tolerate them quite well. Compound GL can be taken in substantial dosage (up to 6 tablets, three times daily) for the initial therapy, following a short trial at low dosage to confirm tolerance and suitability.