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Backbone is a warm formula intended to treat patients who present with kidney Yang deficiency. General signs, other than those indicated above, include cold limbs, fatigue, pale face color, a pale tongue, a deep, weak, slow pulse, spiritual lassitude, and weakness and pain in the low back or knees. The formula is especially effective in treating low back pain and urogenital/sexual dysfunctions that are commonly part of kidney deficiency patterns. While addressing the primary pattern of Yang deficiency, Backbone also includes agents to dispel cold and damp and to move blood in order to eliminate stagnation in the low back, thus making the formula effective for chronic problems.