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Critical to the excitatory pathways are three neurotransmitters: dopamine, epinephrine and norepinephrine. This set of neurotransmitters are synthesized by the limbic system and released in the first part of the day. They allow us to be motivated, alert, and engage positively with the world around us. Individuals who have deficient levels of excitatory neurotransmitters are subject to states of depression. They are also vulnerable to dependency to stimulants